Fansidar (Pyrimethamine, Sulfadoxine)
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IMMUNE SYSTEM AND INFLAMMATION: ’ AND T LYMPHOCYTES, PHAGOCYTES AND MACROPHAGES
What is the relationship between ’ and T lymphocytes?
This relationship is one of the most important ones of the immune system. The T cells remember previously identified antigens and usually activate themselves and the ’ cells in the presence of antigens. Antigens are usually recognized by what are called antigen-presenting cells, also known as APCs. These cells are strategically placed in various parts of the body, such as the lungs, the liver, and the prostate. The APCs present the information, derived from a very complex process of recognition, to the T cells, which never forget an antigen. In a more complicated series of steps, antigens can be presented directly to ’ cells. When T cells are activated, the ’ cells respond by specializing their efforts toward the foreign substance. They produce antibodies that target the specific antigens presented to them. This process is called differentiation.
What are phagocytes?
Phagocytes are white blood cells that eat other cells and certain waste products. The word phagocyte is derived from the Greek word phagos, which means “to eat.” They are also called accessory cells.
What are macrophages?
Macrophages are large, mature phagocytes. These cells are essential to the function of the immune system. In some respects, they are also called accessory cells because they indirectly interact with the T and ’ cells of the immune system. Macrophages have many functions: They ingest and destroy foreign bacteria, diseased cells, and other cellular debris. They also send signals to lymphocytes to alert them to the fact that antigens are present. Macrophages are major producers of cytokines, the communication chemicals of the immune system.
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