Aggrenox (Aspirin, DipyridamoIe)
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CHOLESTEROL AND WOMEN: THE SAME BUT DIFFERENT
Women with elevated cholesterol levels generally are as much at risk of heart disease as are men. Both men and women should have a total cholesterol of less than 5.2 mmol/1, an LDL or “bad” cholesterol count of no more than 3.6, and an HDL or “good” cholesterol count of at least 1 to 1.2. For those recovering from a cardiac event, the goals should be even better. To stop the progress of the disease, or even reverse it, the total cholesterol should be in the 3.9-4.6 range, with an LDL of about 2.6.
But when it comes to HDL levels, most women have a decided advantage. Their counts are naturally higher than those in men, and respond more favourably to measures to increase those numbers. The factors that can raise HDL levels include exercise, quitting cigarettes and certain medications.
But before getting too excited about cholesterol levels and making dietary modifications to lower them, it’s important to realise that a woman cannot base her cholesterol risk on total counts alone. That’s because women so frequently have a much higher HDL count. The result is a much different ratio of total cholesterol to HDL, which is a more accurate predictor of risk than total cholesterol alone.
A man with a total cholesterol (TC) of 6.7 and an HDL of 1 has a ratio of 6.7/1 or 6.0. A ratio of more than 4.5 places a man at risk. But a woman with an identical TC of 6.7 who is found to have an HDL level at 1.8 has a ratio of 6.7/1.8 or 3.7. A ratio of more than 4.0 puts a woman at risk. Thus the women in this example would be at no increased risk, even though both the man and woman have exactly the same TC.
There have been instances of women being placed on prescription drugs to lower cholesterol levels when a closer look would have revealed a picture similar to the one described above. Moreover, stringent dietary restrictions may actually have an adverse effect for women, lowering the level of HDL more precipitously than that of the TC. The result would be a deterioration of the risk ratio.
However, elevated cholesterol levels which are not counterbalanced by increases in HDL must be contended with. This is especially important for older women. Dr Castelli has noted that high cholesterol has far more negative impact on females over 65 than those under 65.
Cardio & BloodThat complete cholesterol analysis, which can be done at your doctor’s office or at a clinical laboratory, will also reveal the level of your triglycerides. While the entire picture has not yet been painted, it appears that an elevated trigylceride count has far greater negative impact on women than on men. A normal triglyceride level is between 1.8 and 3.9.
If you find that your triglycerides are up, even though your cholesterol count is normal, you should take steps to get them down. You can do that by increasing your activity level, by increasing the amount of omega-3 fatty acids you consume by way of fish, and by decreasing your intake of alcohol, sugars and saturated fat.
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