Mobic (Meloxicam)

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Mobic (Meloxicam)
FACTORS BRINGING ON MIGRAINE ATTACKS: DIET
Fasting
It is well known that going without food can bring on an attack of migraine. The explanation often given is that, during fasting, the sugar in the blood falls to a low level (hypoglycemia) and that this provokes an attack. In fact, there are normally body reserves which can be converted to glucose during fasting, so that the blood sugar level does not become dangerously low.
When sugar is eaten, the hormone insulin is released. Its action is to lower the blood sugar level, and it does this in both normal subjects and migraine sufferers, but the low levels last longer than expected in the latter group. Sugar is absorbed in the same way in both sufferers and normals but the release of insulin in response is not quite the same. Using a hormone that releases glucose (glucagon) showed that there was a consistently smaller resultant rise of blood glucose in sufferers than in non-sufferers, and that other abnormalities took longer to return to normal.
In spite of these studies, there is no scientific evidence that sufferers from migraine have a lower level of blood sugar than others. It is probable that it is other changes in the blood associated with fasting which are the trigger factors.
Food headaches
We saw that there are chemical substances in certain foods that can cause a headache, e.g. in the Chinese restaurant syndrome (glutamate), the hot-dog headache (nitrites), and other foods that produce headache because of their physical characteristics, e.g. ice-cream headache. These headaches are not usually typically migrainous.
Probably less than 10 per cent of migraine attacks are due to food.
Cheese.
There is no doubt that at some stage in their lives certain sufferers repeatedly get migraine after eating cheese. However, at other times they may not. The substance thought to be responsible is tyramine, but giving this to cheese-reactive patients does not always produce a migraine attack. Interestingly enough, it was more likely to do so if, instead of being swallowed, it was fed into a vein.
Chocolate.
This is another substance that provokes migraine and also contains tyramine. However, it is now thought that another amine, phenyl ethylamine, is more likely to be responsible.
An experiment was performed on four migrainous sufferers who thought their attacks were brought on by chocolate. Each week they took a capsule and for four months recorded their headaches. All the capsules looked alike but some contained chocolate whilst the others contained a non-active substance (lactose). The ‘guinea-pigs’, who happened to be doctors, did not know which was which and, at the end of four months, the number of headaches following each type of capsule was found to be the same. This experiment shows how cautious we should be when apportioning blame to trigger factors.
*26/152/5*

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